Case 147:   Cirrhosis

Diagnostic Category:

Clinical Presentation:

56 year old woman with cirrhosis from primary biliary cirrhosis.

CT: Vessel penetration sign

Imaging Findings:

Multiphase CT reveals a large hypovascular regenerative nodule in segment 6, which has mild mass effect on the medially adjacent portal triad. Note the small central portal venous vessel within the lesion ("vessel penetration sign", typical for absence of neoplasm, best seen on the last image). After liver transplantation, pathology of the explant was negative for neoplasm.