Case 32:   Primary Sclerosing Cholangitis (PSC)

Diagnostic Category:

Clinical Presentation:

68 year old woman with elevated liver function tests.

CT: Typical: atrophic right lobe, prominent caudate lobe

Imaging Findings:

Typical pattern of hepatic atrophy and regeneration on CT representing primary sclerosing cholangitis (PSC): predominance of peripheral segmental atrophy with complete shrinkage of the right lobe, and compensatory hypertrophy of central segments including the caudate lobe. Differences of biliary calibers, typical for this disease, are not well appreciated on this set of images.